- Brigantine Lighthouse – Constructed by the Island Development Real Estate Company in 1926 as part of an effort to attract residents to the island, the structure was too far from shore and too low to be used as a functioning lighthouse and has been used over the years as headquarters for the Brigantine Police Department, as a museum and as a gift shop, in addition to be a central identifying symbol of the city.
- Marine Mammal Stranding Center – Established in 1978 as the state’s only marine stranding center, the center rehabilitates and releases stranded marine mammals and sea turtles, rescuing more than 3,900 whales, dolphins, seals and sea turtles since it was formed.
- Part of the Edwin B. Forsythe National Wildlife Refuge is located on the northern end of Brigantine Island. The Refuge provides crucial habitat for many different types of endangered or threatened birds, including the American bald eagle, peregrine falcon, American black duck, and the piping plover.
- The Brigantine Hotel, still standing on the Atlantic coast side of the island, was an early integrated hotel starting in the 1940s, and was owned for a period by Father Divine‘s International Peace Mission movement.